MARKET

PALI

PALI

Palisade Bio Inc
NASDAQ
1.520
+0.010
+0.66%
Opening 14:46 01/22 EST
OPEN
1.490
PREV CLOSE
1.510
HIGH
1.550
LOW
1.340
VOLUME
263.01K
TURNOVER
--
52 WEEK HIGH
22.35
52 WEEK LOW
1.340
MARKET CAP
4.20M
P/E (TTM)
-0.1010
1D
5D
1M
3M
1Y
5Y
1D
Weekly Report: what happened at PALI last week (0113-0117)?
Weekly Report · 2d ago
Palisade Bio Completed All Five Planned Single Ascending Dose Cohorts And The Commencement Of The Multiple Ascending Dose Cohorts In Its Ongoing Phase 1a/b Study Of PALI-2108 For Ulcerative Colitis, Topline Data Expected In 1H Of 2025
Benzinga · 6d ago
Palisade Bio completes all five SAD cohorts, advanced MAD cohorts for PALI-2108
TipRanks · 6d ago
PALISADE BIO COMPLETES ALL FIVE SAD COHORTS AND ADVANCES TO MAD COHORTS OF PHASE 1A/B STUDY OF PALI-2108 FOR TREATMENT OF ULCERATIVE COLITIS
Reuters · 6d ago
Weekly Report: what happened at PALI last week (0106-0110)?
Weekly Report · 01/13 09:44
Weekly Report: what happened at PALI last week (1230-0103)?
Weekly Report · 01/06 09:46
PALISADE BIO ANNOUNCES INDUCEMENT GRANT UNDER NASDAQ LISTING RULE 5635(C)(4)
Reuters · 01/03 22:20
Weekly Report: what happened at PALI last week (1223-1227)?
Weekly Report · 12/30/2024 09:44
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About PALI
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Palisade Bio, Inc. is a biopharmaceutical company focused on developing novel therapeutics for serious chronic gastrointestinal diseases. It is engaged in advancing a PALI-2108 for the treatment of IBD, including UC and CD and are researching PALI-1908. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract. UC primarily affects the colon and the rectum. CD can affect any part of the gastrointestinal tract, from the mouth to the anus. PALI-2108 is a prodrug PDE4 inhibitor that operates through a mechanism within colon tissues, targeting the key enzyme phosphodiesterase-4 (PDE4). This enzyme is pivotal in cAMP hydrolysis, and by inhibiting PDE4, intracellular cAMP levels are elevated. This elevation leads to the downregulation of inflammatory cytokines and a reduction in the expression of cell adhesion molecules. By modulating these processes, PALI-2108 prevents the local infiltration and activation of inflammatory cells in the colon tissues.
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